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Piwi suppresses transcription of Brahma-dependent transposons via Maelstrom in ovarian somatic cells

Drosophila Piwi associates with PIWI-interacting RNAs (piRNAs) and represses transposons transcriptionally through heterochromatinization; however, this process is poorly understood. Here, we identify Brahma (Brm), the core adenosine triphosphatase of the SWI/SNF chromatin remodeling complex, as a n...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Onishi, Ryo, Sato, Kaoru, Murano, Kensaku, Negishi, Lumi, Siomi, Haruhiko, Siomi, Mikiko C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732180/
https://ncbi.nlm.nih.gov/pubmed/33310860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz7420
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