Armitage determines Piwi−piRISC processing from precursor formation and quality control to inter‐organelle translocation

Piwi and piRNA form the piRNA‐induced silencing complex (piRISC) to repress transposons. In the current model, Armitage (Armi) brings the Piwi–piRISC precursor (pre‐piRISC) to mitochondria, where Zucchini‐dependent piRISC maturation occurs. Here, we show that Armi is necessary for Piwi–pre‐piRISC fo...

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Publicado en:EMBO Rep
Main Authors: Yamashiro, Haruna, Negishi, Mayu, Kinoshita, Tatsuki, Ishizu, Hirotsugu, Ohtani, Hitoshi, Siomi, Mikiko C
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001504/
https://ncbi.nlm.nih.gov/pubmed/31833223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948769
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