Armitage determines Piwi−piRISC processing from precursor formation and quality control to inter‐organelle translocation

Piwi and piRNA form the piRNA‐induced silencing complex (piRISC) to repress transposons. In the current model, Armitage (Armi) brings the Piwi–piRISC precursor (pre‐piRISC) to mitochondria, where Zucchini‐dependent piRISC maturation occurs. Here, we show that Armi is necessary for Piwi–pre‐piRISC fo...

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Bibliographic Details
Published in:EMBO Rep
Main Authors: Yamashiro, Haruna, Negishi, Mayu, Kinoshita, Tatsuki, Ishizu, Hirotsugu, Ohtani, Hitoshi, Siomi, Mikiko C
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2019
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7001504/
https://ncbi.nlm.nih.gov/pubmed/31833223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948769
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