Roles for the Yb body components Armitage and Yb in primary piRNA biogenesis in Drosophila

PIWI-interacting RNAs (piRNAs) protect genome integrity from transposons. In Drosophila ovarian somas, primary piRNAs are produced and loaded onto Piwi. Here, we describe roles for the cytoplasmic Yb body components Armitage and Yb in somatic primary piRNA biogenesis. Armitage binds to Piwi and is r...

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Détails bibliographiques
Auteurs principaux: Saito, Kuniaki, Ishizu, Hirotsugu, Komai, Miharu, Kotani, Hazuki, Kawamura, Yoshinori, Nishida, Kazumichi M., Siomi, Haruhiko, Siomi, Mikiko C.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2010
Sujets:
Research Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975925/
https://ncbi.nlm.nih.gov/pubmed/20966047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1989510
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