Nerve growth factor potentiates the neurotoxicity of beta amyloid.
The role of growth factors in the pathogenesis of Alzheimer disease is unknown. The beta-amyloid protein accumulates abnormally in the brain in Alzheimer disease and is neurotoxic to differentiated hippocampal neurons in culture. Nerve growth factor (NGF) increased the neurotoxic potency of a beta-a...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1990
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.22.9020 |
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