An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P.

Deposition of the beta-amyloid protein in senile plaques is a pathologic hallmark of Alzheimer disease (AD). Focal deposition of beta amyloid in the adult rat cerebral cortex caused profound neurodegenerative changes, including neuronal loss and degenerating neurons and neurites. Chronic induction o...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kowall, N W, Beal, M F, Busciglio, J, Duffy, L K, Yankner, B A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52271/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1714596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.7247
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