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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

beta-Amyloid (beta A) is normally produced as a nontoxic soluble peptide. In Alzheimer disease, beta A aggregates and accumulates in the brain as inert diffuse plaques or compact plaques associated with neurodegenerative changes. To determine the relationship of neurotoxicity to the physical state o...

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Podrobná bibliografie
Hlavní autoři: Lorenzo, A, Yankner, B A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC45413/
https://ncbi.nlm.nih.gov/pubmed/7991613
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