Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells.

The cellular mechanism underlying the generation of beta-amyloid in Alzheimer disease and its relationship to the normal metabolism of the amyloid precursor protein are unknown. In this report, we show that 3- and 4-kDa peptides derived from amyloid precursor protein are normally secreted. Epitope m...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Busciglio, J, Gabuzda, D H, Matsudaira, P, Yankner, B A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46027/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8446635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.5.2092
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!