Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells.
The cellular mechanism underlying the generation of beta-amyloid in Alzheimer disease and its relationship to the normal metabolism of the amyloid precursor protein are unknown. In this report, we show that 3- and 4-kDa peptides derived from amyloid precursor protein are normally secreted. Epitope m...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46027/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8446635/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.5.2092 |
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