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Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells.

The cellular mechanism underlying the generation of beta-amyloid in Alzheimer disease and its relationship to the normal metabolism of the amyloid precursor protein are unknown. In this report, we show that 3- and 4-kDa peptides derived from amyloid precursor protein are normally secreted. Epitope m...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Busciglio, J, Gabuzda, D H, Matsudaira, P, Yankner, B A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1993
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC46027/
https://ncbi.nlm.nih.gov/pubmed/8446635
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