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Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation.

The major component of the cerebral plaques in Alzheimer disease is the beta-amyloid peptide, but serine proteinase inhibitors like alpha 1-antichymotrypsin (ACT) are also present. Their role in the pathogenesis of amyloid formation is unsettled. In addition to their function as proteinase inhibitor...

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Autors principals: Eriksson, S, Janciauskiene, S, Lannfelt, L
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC42805/
https://ncbi.nlm.nih.gov/pubmed/7892264
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