Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation.
The major component of the cerebral plaques in Alzheimer disease is the beta-amyloid peptide, but serine proteinase inhibitors like alpha 1-antichymotrypsin (ACT) are also present. Their role in the pathogenesis of amyloid formation is unsettled. In addition to their function as proteinase inhibitor...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7892264/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.6.2313 |
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