Regorafenib overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter in colorectal cancer: In vitro and in vivo study

Chemotherapeutic multidrug resistance (MDR) is a significant challenge to overcome in clinic practice. Several mechanisms contribute to MDR, one of which is the augmented drug efflux induced by the upregulation of ABCB1 in cancer cells. Regorafenib, a multikinase inhibitor targeting the RAS/RAF/MEK/...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Lett
Asıl Yazarlar: Wang, Yi-Jun, Zhang, Yun-Kai, Zhang, Guan-Nan, Al Rihani, Sweilem B., Wei, Meng-Ning, Gupta, Pranav, Zhang, Xiao-Yu, Shukla, Suneet, Ambudkar, Suresh V., Kaddoumi, Amal, Shi, Zhi, Chen, Zhe-Sheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507680/
https://ncbi.nlm.nih.gov/pubmed/28302530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.03.011
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller