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Inflammation dependent mTORC1 signaling interferes with the switch from keratinocyte proliferation to differentiation
Psoriasis is a frequent and often severe inflammatory skin disease, characterized by altered epidermal homeostasis. Since we found previously that Akt/mTOR signaling is hyperactivated in psoriatic skin, we aimed at elucidating the role of aberrant mTORC1 signaling in this disease. We found that unde...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5507280/ https://ncbi.nlm.nih.gov/pubmed/28700632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180853 |
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