Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

How metabolic pathways required for epidermal tissue growth and remodeling influence the ability of keratinocytes to survive stressful conditions is still largely unknown. The mechanistic target of rapamycin complex 2 (mTORC2) regulates growth and metabolism of several tissues, but its functions in...

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Bibliografski detalji
Izdano u:Cell Death Differ
Glavni autori: Tassone, Beatrice, Saoncella, Stefania, Neri, Francesco, Ala, Ugo, Brusa, Davide, Magnuson, Mark A, Provero, Paolo, Oliviero, Salvatore, Riganti, Chiara, Calautti, Enzo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Original Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384034/
https://ncbi.nlm.nih.gov/pubmed/28211872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.8
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