Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis

How metabolic pathways required for epidermal tissue growth and remodeling influence the ability of keratinocytes to survive stressful conditions is still largely unknown. The mechanistic target of rapamycin complex 2 (mTORC2) regulates growth and metabolism of several tissues, but its functions in...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Tassone, Beatrice, Saoncella, Stefania, Neri, Francesco, Ala, Ugo, Brusa, Davide, Magnuson, Mark A, Provero, Paolo, Oliviero, Salvatore, Riganti, Chiara, Calautti, Enzo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384034/
https://ncbi.nlm.nih.gov/pubmed/28211872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.8
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