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In vitro and in vivo fitness costs associated with Mycobacterium tuberculosis RpoB mutation H526D
AIM: There is controversy regarding the potential fitness costs of rifampicin (RIF) resistance-conferring mutations in the Mycobacterium tuberculosis (Mtb) rpoB gene. We characterized the pathogenicity of an Mtb RpoB H526D mutant. MATERIALS & METHODS: A mutant containing the RpoB H526D mutation...
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| Publicado no: | Future Microbiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Medicine Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5506874/ https://ncbi.nlm.nih.gov/pubmed/28343421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fmb-2017-0022 |
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