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Effect of rpoB Mutations Conferring Rifampin Resistance on Fitness of Mycobacterium tuberculosis
Rifampin is a major drug used in the treatment of tuberculosis infections, and increasing rifampin resistance represents a worldwide clinical problem. Resistance to rifampin is caused by mutations in the rpoB gene, encoding the β-subunit of RNA polymerase. We examined the effect of three different r...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC375340/ https://ncbi.nlm.nih.gov/pubmed/15047531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1289-1294.2004 |
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