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Effect of rpoB Mutations Conferring Rifampin Resistance on Fitness of Mycobacterium tuberculosis

Rifampin is a major drug used in the treatment of tuberculosis infections, and increasing rifampin resistance represents a worldwide clinical problem. Resistance to rifampin is caused by mutations in the rpoB gene, encoding the β-subunit of RNA polymerase. We examined the effect of three different r...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Mariam, Deneke H., Mengistu, Yohannes, Hoffner, Sven E., Andersson, Dan I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC375340/
https://ncbi.nlm.nih.gov/pubmed/15047531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1289-1294.2004
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