Upregulation of the Phthiocerol Dimycocerosate Biosynthetic Pathway by Rifampin-Resistant, rpoB Mutant Mycobacterium tuberculosis

Multidrug-resistant tuberculosis has emerged as a major threat to tuberculosis control. Phylogenetically related rifampin-resistant actinomycetes with mutations mapping to clinically dominant Mycobacterium tuberculosis mutations in the rpoB gene show upregulation of gene networks encoding secondary...

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Main Authors: Bisson, Gregory P., Mehaffy, Carolina, Broeckling, Corey, Prenni, Jessica, Rifat, Dalin, Lun, Desmond S., Burgos, Marcos, Weissman, Drew, Karakousis, Petros C., Dobos, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497527/
https://ncbi.nlm.nih.gov/pubmed/23002228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01013-12
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