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Inducible knockdown of pregnancy‐associated plasma protein‐A gene expression in adult female mice extends life span
Pregnancy‐associated plasma protein‐A (PAPP‐A) knockout (KO) mice, generated through homologous recombination in embryonic stem cells, have a significantly increased lifespan compared to wild‐type littermates. However, it is unknown whether this longevity advantage would pertain to PAPP‐A gene delet...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5506424/ https://ncbi.nlm.nih.gov/pubmed/28600811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12624 |
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