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Inducible Reduction in Pregnancy-Associated Plasma Protein-A Gene Expression Inhibits Established Atherosclerotic Plaque Progression in Mice

Pregnancy-associated plasma protein-A (PAPP-A) is a novel zinc metalloproteinase implicated in cardiovascular disease. The aim of this study was to determine whether a reduction in PAPP-A expression in the adult affects the progression of established atherosclerotic plaque. Apolipoprotein E-null mic...

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Main Authors: Bale, Laurie K., Chakraborty, Suban, Conover, Cheryl A.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959602/
https://ncbi.nlm.nih.gov/pubmed/24506074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2110
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