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Preclinical analgesic and safety evaluation of the GalR2-preferring analog, NAX 810-2
The potential clinical utility of galanin peptidic analogs has been hindered by poor metabolic stability, lack of brain penetration, and hyperglycemia. In addition to possessing potent anticonvulsant efficacy, galanin analogs are analgesic in various assays. The purpose of these studies was to evalu...
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| Published in: | Neurochem Res |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5505798/ https://ncbi.nlm.nih.gov/pubmed/28382595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-017-2229-5 |
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