IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells

Enhanced chemoresistance is, among other factors, believed to be responsible for treatment failure and tumor relapse in patients with epithelial ovarian cancer (EOC). Here, we exposed EOC cells to interleukin-6 (IL-6) to activate oncogenic STAT3, which directly repressed miR-204 via a conserved STAT...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Long, Lulu, Chen, Xiaofang, Feng, Fan, Liu, Yueqin, Zhao, Peiqing, Xu, Yue, Li, Mei, Xu, Wenlin, Li, Yuefeng
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503602/
https://ncbi.nlm.nih.gov/pubmed/28388577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16610
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