IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells

Enhanced chemoresistance is, among other factors, believed to be responsible for treatment failure and tumor relapse in patients with epithelial ovarian cancer (EOC). Here, we exposed EOC cells to interleukin-6 (IL-6) to activate oncogenic STAT3, which directly repressed miR-204 via a conserved STAT...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Long, Lulu, Chen, Xiaofang, Feng, Fan, Liu, Yueqin, Zhao, Peiqing, Xu, Yue, Li, Mei, Xu, Wenlin, Li, Yuefeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503602/
https://ncbi.nlm.nih.gov/pubmed/28388577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16610
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