IL-6R/STAT3/miR-204 feedback loop contributes to cisplatin resistance of epithelial ovarian cancer cells

Enhanced chemoresistance is, among other factors, believed to be responsible for treatment failure and tumor relapse in patients with epithelial ovarian cancer (EOC). Here, we exposed EOC cells to interleukin-6 (IL-6) to activate oncogenic STAT3, which directly repressed miR-204 via a conserved STAT...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Long, Lulu, Chen, Xiaofang, Feng, Fan, Liu, Yueqin, Zhao, Peiqing, Xu, Yue, Li, Mei, Xu, Wenlin, Li, Yuefeng
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503602/
https://ncbi.nlm.nih.gov/pubmed/28388577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16610
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares