IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis

Members of the miR-34 family are induced by the tumor suppressor p53 and are known to inhibit epithelial-to-mesenchymal transition (EMT) and therefore presumably suppress the early phases of metastasis. Here, we determined that exposure of human colorectal cancer (CRC) cells to the cytokine IL-6 act...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rokavec, Matjaz, Öner, Meryem Gülfem, Li, Huihui, Jackstadt, Rene, Jiang, Longchang, Lodygin, Dmitri, Kaller, Markus, Horst, David, Ziegler, Paul K., Schwitalla, Sarah, Slotta-Huspenina, Julia, Bader, Franz G., Greten, Florian R., Hermeking, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973098/
https://ncbi.nlm.nih.gov/pubmed/24642471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73531
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados