Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype

BACKGROUND: How exosomal microRNAs (miRNAs) derived from macrophages contribute to the development of drug resistance in the context of the hypoxic tumor microenvironment in epithelial ovarian cancer (EOC) remains poorly understood. METHODS: The miRNA levels were detected by qRT-PCR. Protein levels...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Exp Clin Cancer Res
Autori principali: Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Yang, Meiling, Wei, Hong, Chen, Qi, Feng, Fan, Liu, Yueqin, Xu, Wenlin, Li, Yuefeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377760/
https://ncbi.nlm.nih.gov/pubmed/30770776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1095-1
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