Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype

BACKGROUND: How exosomal microRNAs (miRNAs) derived from macrophages contribute to the development of drug resistance in the context of the hypoxic tumor microenvironment in epithelial ovarian cancer (EOC) remains poorly understood. METHODS: The miRNA levels were detected by qRT-PCR. Protein levels...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Yang, Meiling, Wei, Hong, Chen, Qi, Feng, Fan, Liu, Yueqin, Xu, Wenlin, Li, Yuefeng
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377760/
https://ncbi.nlm.nih.gov/pubmed/30770776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1095-1
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