Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype

BACKGROUND: How exosomal microRNAs (miRNAs) derived from macrophages contribute to the development of drug resistance in the context of the hypoxic tumor microenvironment in epithelial ovarian cancer (EOC) remains poorly understood. METHODS: The miRNA levels were detected by qRT-PCR. Protein levels...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Zhu, Xiaolan, Shen, Huiling, Yin, Xinming, Yang, Meiling, Wei, Hong, Chen, Qi, Feng, Fan, Liu, Yueqin, Xu, Wenlin, Li, Yuefeng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377760/
https://ncbi.nlm.nih.gov/pubmed/30770776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1095-1
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