Antiproliferative effect of ZSTK474 alone or in combination with chemotherapeutic drugs on HL60 and HL60/ADR cells

While chemotherapy remains to be one of the main approaches in the clinical treatment of acute myeloid leukemia (AML), multidrug resistance (MDR) has become a serious problem which limits the therapeutic efficacy. The important roles of the PI3K/Akt pathway in modulating cell proliferation and MDR s...

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Publicado en:Oncotarget
Autores principales: Zhou, Qianxiang, Chen, Yali, Zhang, Lei, Zhong, Yuxu, Zhang, Zhe, Wang, Ran, Jin, Meihua, Gong, Min, Qiu, Yuling, Kong, Dexin
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503595/
https://ncbi.nlm.nih.gov/pubmed/28388564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16589
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