In Vitro Antileukemia Activity of ZSTK474 on K562 and Multidrug Resistant K562/A02 Cells

Chronic myelogenous leukemia (CML) is a malignant hematological disorder mainly caused by the Bcr-Abl tyrosine kinase. While Bcr-Abl inhibitors including Imatinib showed antitumor efficacy on many CML patients, resistance was frequently reported in recent years. Therefore, novel drugs for CML are st...

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Publicat a:Int J Biol Sci
Autors principals: Zhou, Qianxiang, Chen, Yali, Chen, Xi, Zhao, Wennan, Zhong, Yuxu, Wang, Ran, Jin, Meihua, Qiu, Yuling, Kong, Dexin
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870707/
https://ncbi.nlm.nih.gov/pubmed/27194941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.14878
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