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Stellettin B induces apoptosis in human chronic myeloid leukemia cells via targeting PI3K and Stat5

Novel agents are still urgently expected for therapy of chronic myeloid leukemia (CML). The in vitro anti-leukemia activity of Stellettin B (Stel B), a triterpenoid we isolated from marine sponge Jaspis stellifera, on human CML K562 and KU812 cells was recently investigated. Stel B inhibited K562 an...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Chen, Yali, Zhou, Qianxiang, Zhang, Lei, Zhong, Yuxu, Fan, Guanwei, Zhang, Zhe, Wang, Ran, Jin, Meihua, Qiu, Yuling, Kong, Dexin
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5438702/
https://ncbi.nlm.nih.gov/pubmed/28423649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15957
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