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Proximal clustering between BK and Ca(V)1.3 channels promotes functional coupling and BK channel activation at low voltage

Ca(V)-channel dependent activation of BK channels is critical for feedback control of both calcium influx and cell excitability. Here we addressed the functional and spatial interaction between BK and Ca(V)1.3 channels, unique Ca(V)1 channels that activate at low voltages. We found that when BK and...

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Pubblicato in:eLife
Autori principali: Vivas, Oscar, Moreno, Claudia M, Santana, Luis F, Hille, Bertil
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503510/
https://ncbi.nlm.nih.gov/pubmed/28665272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28029
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