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Proximal clustering between BK and Ca(V)1.3 channels promotes functional coupling and BK channel activation at low voltage

Ca(V)-channel dependent activation of BK channels is critical for feedback control of both calcium influx and cell excitability. Here we addressed the functional and spatial interaction between BK and Ca(V)1.3 channels, unique Ca(V)1 channels that activate at low voltages. We found that when BK and...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Vivas, Oscar, Moreno, Claudia M, Santana, Luis F, Hille, Bertil
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503510/
https://ncbi.nlm.nih.gov/pubmed/28665272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28029
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