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Graded Ca(2+)/calmodulin-dependent coupling of voltage-gated Ca(V)1.2 channels
In the heart, reliable activation of Ca(2+) release from the sarcoplasmic reticulum during the plateau of the ventricular action potential requires synchronous opening of multiple Ca(V)1.2 channels. Yet the mechanisms that coordinate this simultaneous opening during every heartbeat are unclear. Here...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360655/ https://ncbi.nlm.nih.gov/pubmed/25714924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05608 |
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