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Graded Ca(2+)/calmodulin-dependent coupling of voltage-gated Ca(V)1.2 channels

In the heart, reliable activation of Ca(2+) release from the sarcoplasmic reticulum during the plateau of the ventricular action potential requires synchronous opening of multiple Ca(V)1.2 channels. Yet the mechanisms that coordinate this simultaneous opening during every heartbeat are unclear. Here...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Dixon, Rose E, Moreno, Claudia M, Yuan, Can, Opitz-Araya, Ximena, Binder, Marc D, Navedo, Manuel F, Santana, Luis F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360655/
https://ncbi.nlm.nih.gov/pubmed/25714924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05608
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