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Increased coupled gating of L-type Ca(2+) channels during hypertension and Timothy syndrome

RATIONALE: L-type (Cav1.2) Ca(2+) channels are critical regulators of muscle and neural function. Although Cav1.2 channel activity varies regionally, little is known about the mechanisms underlying this heterogeneity. OBJECTIVE: To test the hypothesis that Cav1.2 channels can gate coordinately. METH...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Navedo, Manuel F., Cheng, Edward P., Yuan, Can, Votaw, Scott, Molkentin, Jeffery D., Scott, John D., Santana, Luis F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834417/
https://ncbi.nlm.nih.gov/pubmed/20110531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.213363
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