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Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies
The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved that compound 6d is a highly potent melanogenesis inhibitor compared to standard kojic acid. The title amides 4a–e and 6a–e were synthesized...
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| 發表在: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Dove Medical Press
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5503496/ https://ncbi.nlm.nih.gov/pubmed/28740364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S137550 |
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