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Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies
The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved that compound 6d is a highly potent melanogenesis inhibitor compared to standard kojic acid. The title amides 4a–e and 6a–e were synthesized...
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| Pubblicato in: | Drug Des Devel Ther |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5503496/ https://ncbi.nlm.nih.gov/pubmed/28740364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S137550 |
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