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Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies
The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved that compound 6d is a highly potent melanogenesis inhibitor compared to standard kojic acid. The title amides 4a–e and 6a–e were synthesized...
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| 出版年: | Drug Des Devel Ther |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Dove Medical Press
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5503496/ https://ncbi.nlm.nih.gov/pubmed/28740364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S137550 |
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