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Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies

The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved that compound 6d is a highly potent melanogenesis inhibitor compared to standard kojic acid. The title amides 4a–e and 6a–e were synthesized...

詳細記述

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書誌詳細
出版年:Drug Des Devel Ther
主要な著者: Abbas, Qamar, Ashraf, Zaman, Hassan, Mubashir, Nadeem, Humaira, Latif, Muhammad, Afzal, Samina, Seo, Sung-Yum
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503496/
https://ncbi.nlm.nih.gov/pubmed/28740364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S137550
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