Development of highly potent melanogenesis inhibitor by in vitro, in vivo and computational studies

The present work describes the synthesis of few hydroxylated amide derivatives as melanogenesis inhibitors. In vitro, in vivo and computational studies proved that compound 6d is a highly potent melanogenesis inhibitor compared to standard kojic acid. The title amides 4a–e and 6a–e were synthesized...

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Bibliografiska uppgifter
I publikationen:Drug Des Devel Ther
Huvudupphovsmän: Abbas, Qamar, Ashraf, Zaman, Hassan, Mubashir, Nadeem, Humaira, Latif, Muhammad, Afzal, Samina, Seo, Sung-Yum
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503496/
https://ncbi.nlm.nih.gov/pubmed/28740364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S137550
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