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Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70)

Heat shock protein 70 (Hsp70) is a molecular chaperone that plays critical roles in protein homeostasis. Hsp70’s chaperone activity is coordinated by intra-molecular interactions between its two domains, as well as inter-molecular interactions between Hsp70 and its co-chaperones. Each of these conta...

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Detalhes bibliográficos
Publicado no:Curr Top Med Chem
Main Authors: Li, Xiaokai, Shao, Hao, Taylor, Isabelle R., Gestwicki, Jason E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502483/
https://ncbi.nlm.nih.gov/pubmed/27072701
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