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Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase β
With the formidable growth in the volume of genetic information, it has become essential to identify and characterize mutations in macromolecules not only to predict contributions to disease processes but also to guide the design of therapeutic strategies. While mutations of certain residues have a...
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| Veröffentlicht in: | Biochemistry |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501977/ https://ncbi.nlm.nih.gov/pubmed/28402631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01287 |
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