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Alpha 2 Na(+),K(+)-ATPase silencing induces loss of inflammatory response and ouabain protection in glial cells
Ouabain (OUA) is a cardiac glycoside that binds to Na(+),K(+)-ATPase (NKA), a conserved membrane protein that controls cell transmembrane ionic concentrations and requires ATP hydrolysis. At nM concentrations, OUA activates signaling pathways that are not related to its typical inhibitory effect on...
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| Foilsithe in: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501845/ https://ncbi.nlm.nih.gov/pubmed/28687727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05075-9 |
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