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Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells

BACKGROUND: Parkinson’s disease (PD) is a neurodegenerative disease with characteristics and symptoms that are well defined. Nevertheless, its aetiology remains unknown. PD is characterized by the presence of Lewy bodies inside neurons. α-Synuclein (α-syn) is a soluble protein present in the pre-syn...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Yshii, Lidia M., Denadai-Souza, Alexandre, Vasconcelos, Andrea R., Avellar, Maria Christina W., Scavone, Cristoforo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623263/
https://ncbi.nlm.nih.gov/pubmed/26502720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0412-7
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