Signaling function of Na,K-ATPase induced by ouabain against LPS as an inflammation model in hippocampus

BACKGROUND: Ouabain (OUA) is a newly recognized hormone that is synthesized in the adrenal cortex and hypothalamus. Low doses of OUA can activate a signaling pathway by interaction with Na,K-ATPase, which is protective against a number of insults. OUA has central and peripheral anti-inflammatory eff...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Kinoshita, Paula Fernanda, Yshii, Lidia Mitiko, Vasconcelos, Andrea Rodrigues, Orellana, Ana Maria Marques, Lima, Larissa de Sá, Davel, Ana Paula Couto, Rossoni, Luciana Venturini, Kawamoto, Elisa Mitiko, Scavone, Cristoforo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4307894/
https://ncbi.nlm.nih.gov/pubmed/25551197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0218-z
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