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Extracellular nutrients are required to maintain oncogenic signaling in brain cancer – a critical role for mTORC2

Mutations in growth factor receptor signaling pathways are common in cancer cells, including the highly lethal brain tumor glioblastoma (GBM) where they drive tumor growth through mechanisms including altering the uptake and utilization of nutrients. However, the impact of changes in micro-environme...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioessays
Egile Nagusiak: Masui, Kenta, Shibata, Noriyuki, Cavenee, Webster K., Mischel, Paul S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501721/
https://ncbi.nlm.nih.gov/pubmed/27427440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600026
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