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The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1
Despite being surrounded by diverse nutrients, mammalian cells preferentially metabolize glucose and free amino acids. Recently, Ras-induced macropinocytosis of extracellular proteins was shown to reduce a transformed cell’s dependence on extracellular glutamine. Here, we demonstrate that protein ma...
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| Publicado no: | Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506698/ https://ncbi.nlm.nih.gov/pubmed/26144316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.06.017 |
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