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Extracellular nutrients are required to maintain oncogenic signaling in brain cancer – a critical role for mTORC2
Mutations in growth factor receptor signaling pathways are common in cancer cells, including the highly lethal brain tumor glioblastoma (GBM) where they drive tumor growth through mechanisms including altering the uptake and utilization of nutrients. However, the impact of changes in micro-environme...
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| Udgivet i: | Bioessays |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501721/ https://ncbi.nlm.nih.gov/pubmed/27427440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201600026 |
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