The nature of the GRE influences the screening for GR-activity enhancing modulators

Glucocorticoid resistance (GCR), i.e. unresponsiveness to the beneficial anti-inflammatory activities of the glucocorticoid receptor (GR), poses a serious problem in the treatment of inflammatory diseases. One possible solution to try and overcome GCR, is to identify molecules that prevent or revert...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Dendoncker, Karen, Timmermans, Steven, Van Looveren, Kelly, De Cauwer, Lode, De Bosscher, Karolien, Libert, Claude
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501670/
https://ncbi.nlm.nih.gov/pubmed/28686666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181101
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