Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice

Anemia suppresses liver hepcidin expression to supply adequate iron for erythropoiesis. Erythroferrone mediates hepcidin suppression by anemia, but its mechanism of action remains uncertain. The bone morphogenetic protein (BMP)–SMAD signaling pathway has a central role in hepcidin transcriptional re...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Wang, Chia-Yu, Core, Amanda B., Canali, Susanna, Zumbrennen-Bullough, Kimberly B., Ozer, Sinan, Umans, Lieve, Zwijsen, An, Babitt, Jodie L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2017
Gaiak:
Red Cells, Iron, and Erythropoiesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501149/
https://ncbi.nlm.nih.gov/pubmed/28438754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-12-759423
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