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Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice
Anemia suppresses liver hepcidin expression to supply adequate iron for erythropoiesis. Erythroferrone mediates hepcidin suppression by anemia, but its mechanism of action remains uncertain. The bone morphogenetic protein (BMP)–SMAD signaling pathway has a central role in hepcidin transcriptional re...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501149/ https://ncbi.nlm.nih.gov/pubmed/28438754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-12-759423 |
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