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Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice

Anemia suppresses liver hepcidin expression to supply adequate iron for erythropoiesis. Erythroferrone mediates hepcidin suppression by anemia, but its mechanism of action remains uncertain. The bone morphogenetic protein (BMP)–SMAD signaling pathway has a central role in hepcidin transcriptional re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Wang, Chia-Yu, Core, Amanda B., Canali, Susanna, Zumbrennen-Bullough, Kimberly B., Ozer, Sinan, Umans, Lieve, Zwijsen, An, Babitt, Jodie L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501149/
https://ncbi.nlm.nih.gov/pubmed/28438754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-12-759423
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