Simulations of Membrane-bound Diglycosylated Human Prion Protein Reveal Potential Protective Mechanisms against Misfolding

Antzeko izenburuak

• Characterization of cell-surface prion protein relative to its recombinant analogue: Insights from molecular dynamics simulations of diglycosylated, membrane-bound human prion protein
  nork: DeMarco, Mari L., et al.
  Argitaratua: (2009)
• Molecular Dynamics Simulations Capture the Misfolding of the Bovine Prion Protein at Acidic pH
  nork: Cheng, Chin Jung, et al.
  Argitaratua: (2014)
• Influence of pH on the Human Prion Protein: Insights into the Early Steps of Misfolding
  nork: van der Kamp, Marc W., et al.
  Argitaratua: (2010)
• Pathogenic mutations in the hydrophobic core of the human prion protein can promote structural instability and misfolding
  nork: van der Kamp, Marc W., et al.
  Argitaratua: (2010)
• Different misfolding mechanisms converge on common conformational changes: Human prion protein pathogenic mutants Y218N and E196K
  nork: Jung Cheng, Chin, et al.
  Argitaratua: (2014)