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Simulations of Membrane-bound Diglycosylated Human Prion Protein Reveal Potential Protective Mechanisms against Misfolding
Prion diseases are associated with the misfolding of the prion protein (PrP) from its normal cellular form (PrP(C)) to its infectious scrapie form (PrP(Sc)). Posttranslational modifications of PrP in vivo can play an important role in modulating the process of misfolding. To gain more insight into t...
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| Publicado no: | J Neurochem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500178/ https://ncbi.nlm.nih.gov/pubmed/28407243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.14044 |
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