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Characterization of cell-surface prion protein relative to its recombinant analogue: Insights from molecular dynamics simulations of diglycosylated, membrane-bound human prion protein

The prion protein is responsible for several fatal neurodegenerative diseases via conversion from its normal to disease-related isoform. The recombinant form of the protein is typically studied to investigate the conversion process. This constructs lacks the co- and post-translational modifications...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: DeMarco, Mari L., Daggett, Valerie
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2009
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674387/
https://ncbi.nlm.nih.gov/pubmed/19226372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05892.x
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