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From conversion to aggregation: Protofibril formation of the prion protein
The ability to diagnose and treat prion diseases is limited by our current understanding of the conversion process of the protein from healthy to harmful isoform. Whereas the monomeric, benign species is well characterized, the misfolded conformations responsible for infectivity and neurodegeneratio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC356944/ https://ncbi.nlm.nih.gov/pubmed/14983003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307178101 |
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